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Research on the Relationship between Personal-Organizational Values Fit and Job Involvement of the New

Ai-hua Huang,Guo-tao Guo,Hai-xia Qiu

《工程管理前沿（英文）》 2015年 第2卷 第1期   页码 31-34 doi: 10.15302/J-FEM-2015005

摘要： To improve the management of the new generation of employees, the authors have discussed the relationship between the personal-organizational values fit and job involvement of the new generation of employees, and made perceived organizational support as a mediating variable. The empirical results found that the personal-organizational values fit had a significant positive effect on job involvement of the new generation of employees and the perceived organizational support became as the mediating variable.

关键词： personal-organizational values fit     job involvement     perceived organizational support     new generation of employees    

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A job-insertion heuristic for minimizing the mean flowtime in dynamic flowshops

Guang GUO, Bo WU, Shuzi YANG

《机械工程前沿（英文）》 2011年 第6卷 第2期   页码 197-202 doi: 10.1007/s11465-011-0211-5

摘要：

A new adaptive job-insertion based heuristic is presented to minimize the mean flowtime in a dynamic flowshop consisting of machines. Job orders arrive to the system randomly, and the job arrival or release dates are not known in advance. The heuristic is derived by inserting new jobs into the scheduled sequence as needed when the machine becomes free. Computation results indicate that the proposed heuristic performs 2.7%–10.8% better than the SPT dispatching rule, which is currently one of the most effective methods for minimizing the mean flowtime in dynamic flowshops.

关键词： scheduling     dynamic flowshops     flowtime     heuristic     mean flowtime    

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Industry effect of job hopping: An agent-based simulation of Chinese construction workers

Jide SUN, Mian ZHENG, Martin SKITMORE, Bo XIA, Xincheng WANG

《工程管理前沿（英文）》 2019年 第6卷 第2期   页码 249-261 doi: 10.1007/s42524-019-0014-4

摘要： Job hopping affects the development of industries in terms of efficiency and quality of work. It is a problem for the Chinese construction industry, where excessive job hopping is detrimental to meeting the current daunting challenges involved in the industry’s transformation and efficiency improvement. To provide an exhaustive analysis of this effect, game theory is combined with social relationship networks to create an agent-based simulation model. Simulation results indicate that the frequent job moves of Chinese construction workers have a negative effect on their skill development, employment, and worker relationships, as well as results in sharp increase in employer labor costs. The findings point to the need to act for the benefit of workers and employers and maintain the development of the industry.

关键词： job hopping     agent-based simulation     construction industry     effect     China    

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Analysis of dispatching rules in a stochastic dynamic job shop manufacturing system with sequence-dependent

Pankaj SHARMA,Ajai JAIN

《机械工程前沿（英文）》 2014年 第9卷 第4期   页码 380-389 doi: 10.1007/s11465-014-0315-9

摘要：

Stochastic dynamic job shop scheduling problem with consideration of sequence-dependent setup times are among the most difficult classes of scheduling problems. This paper assesses the performance of nine dispatching rules in such shop from makespan, mean flow time, maximum flow time, mean tardiness, maximum tardiness, number of tardy jobs, total setups and mean setup time performance measures viewpoint. A discrete event simulation model of a stochastic dynamic job shop manufacturing system is developed for investigation purpose. Nine dispatching rules identified from literature are incorporated in the simulation model. The simulation experiments are conducted under due date tightness factor of 3, shop utilization percentage of 90 % and setup times less than processing times. Results indicate that shortest setup time (SIMSET) rule provides the best performance for mean flow time and number of tardy jobs measures. The job with similar setup and modified earliest due date (JMEDD) rule provides the best performance for makespan, maximum flow time, mean tardiness, maximum tardiness, total setups and mean setup time measures.

关键词： scheduling     stochastic dynamic job shop     sequence-dependent setup times     dispatching rule     simulation    

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Energy-aware fuzzy job-shop scheduling for engine remanufacturing at the multi-machine level

Jiali ZHAO, Shitong PENG, Tao LI, Shengping LV, Mengyun LI, Hongchao ZHANG

《机械工程前沿（英文）》 2019年 第14卷 第4期   页码 474-488 doi: 10.1007/s11465-019-0560-z

摘要： The rise of the engine remanufacturing industry has resulted in increased possibilities of energy conservation during the remanufacturing process, and scheduling could exert significant effects on the energy performance of manufacturing systems. However, only a few studies have specifically addressed energy-efficient scheduling for remanufacturing. Considering the uncertain processing time and routes and the operation characteristics of remanufacturing, we used the crankshaft as an illustrative case and built a fuzzy job-shop scheduling model to minimize the energy consumption during remanufacturing. An improved adaptive genetic algorithm was developed by using the hormone modulation mechanism to deal with the scheduling problem that simultaneously involves parallel machines, batch machines, and uncertain processing routes and time. The algorithm demonstrated superior performance in terms of optimal value, run time, and convergent generation in comparison with other algorithms. Computational results indicated that the optimal scheduling scheme is expected to generate 1.7 kW∙h of energy saving for the investigated problem size. In addition, the scheme could improve the energy efficiency of the crankshaft remanufacturing process by approximately 5%. This study provides a basis for production managers to improve the sustainability of remanufacturing through energy-aware scheduling.

关键词： remanufacturing scheduling     adaptive genetic algorithm     energy efficiency     sustainable remanufacturing     hormone modulation mechanism    

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Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock

null

《医学前沿（英文）》 2014年 第8卷 第2期   页码 254-258 doi: 10.1007/s11684-014-0319-1

摘要：

Mantle cell lymphoma is an aggressive subtype of B cell non-Hodgkin lymphoma. It can progress to leukemic phase but frank leukemic picture at initial presentation is not common. Leukemic phase indicates advance stage of the disease and generally associated with extensive extra-nodal involvement. Pericardial invasion has been reported, however we could not find a report of myocardial infiltration by this disease since the appraisal of the term “mantle cell lymphoma” in 1992. Here we report a case of cardiac involvement by mantle cell leukemia leading to cardiogenic shock which complicates the treatment decisions.

关键词： mantle cell lymphoma     bendamustine     cardiogenic shock    

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Astragaloside IV suppresses post-ischemic natural killer cell infiltration and activation in the brain: involvement

Baokai Dou, Shichun Li, Luyao Wei, Lixin Wang, Shiguo Zhu, Zhengtao Wang, Zunji Ke, Kaixian Chen, Zhifei Wang

《医学前沿（英文）》 2021年 第15卷 第1期   页码 79-90 doi: 10.1007/s11684-020-0783-8

摘要： Natural killer (NK) cells, a type of cytotoxic lymphocytes, can infiltrate into ischemic brain and exacerbate neuronal cell death. Astragaloside IV (ASIV) is the major bioactive ingredient of , a Chinese herbal medicine, and possesses potent immunomodulatory and neuroprotective properties. This study investigated the effects of ASIV on post-ischemic brain infiltration and activation of NK cells. ASIV reduced brain infarction and alleviated functional deficits in MCAO rats, and these beneficial effects persisted for at least 7 days. Abundant NK cells infiltrated into the ischemic hemisphere on day 1 after brain ischemia, and this infiltration was suppressed by ASIV. Strikingly, ASIV reversed NK cell deficiency in the spleen and blood after brain ischemia. ASIV inhibited astrocyte-derived CCL2 upregulation and reduced CCR2 NK cell levels in the ischemic brain. Meanwhile, ASIV attenuated NK cell activating receptor NKG2D levels and reduced interferon-γ production. ASIV restored acetylation of histone H3 and the p65 subunit of nuclear factor-κB in the ischemic brain, suggesting inhibition of histone deacetylase (HDAC). Simultaneously, ASIV prevented p65 nuclear translocation. The effects of ASIV on reducing CCL2 production, restoring acetylated p65 levels and preventing p65 nuclear translocation were mimicked by valproate, an HDAC inhibitor, in astrocytes subjected to oxygen-glucose deprivation. Our findings suggest that ASIV inhibits post-ischemic NK cell brain infiltration and activation and reverses NK cell deficiency in the periphery, which together contribute to the beneficial effects of ASIV against brain ischemia. Furthermore, ASIV’s effects on suppressing NK cell brain infiltration and activation may involve HDAC inhibition.

关键词： astragaloside IV     brain ischemia     natural killer cells     histone deacetylase     nuclear factor-κB    

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Perception of people for the risk of Tianwan nuclear power plant

Lei HUANG, Jun BI, Bing ZHANG, Fengying LI, Changsheng QU,

《环境科学与工程前沿（英文）》 2010年 第4卷 第1期   页码 73-81 doi: 10.1007/s11783-009-0151-z

摘要： A questionnaire survey of residents’ risk perceptions related to Taiwan nuclear power plant in China was carried out to explore the determining factors that affect individual risk perception. This study proposed to pursue a more comprehensive understanding of factors that affected individual risk perception to nuclear power plants. Covariance structure analysis was conducted using risk perceptions of nuclear power as dependent variable and including interest and knowledge levels of nuclear power, acceptability, benefit perception, trust in nuclear power operation, and trust in government as independent variables. The use of the hypothesis of Elaboration likelihood model (ELM) was also proposed. The results showed that persons with higher levels of interest and knowledge of nuclear power had their own perceptions of risk closely associated with acceptability and potential benefits of nuclear power. In contrast, persons with no interest in and knowledge of nuclear power would have risk perceptions related to their trust in nuclear operation and the government, which partially supported the ELM hypothesis. All these results indicated that the government in China plays an important role in rational risk perceptions, and well-designed communication of risks will help the public to be involved in risk management and improve people’s rational acceptance of risk.

关键词： nuclear power     risk perception     public involvement     covariance structure analysis     China    

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Different sites of extranodal involvement may affect the survival of patients with relapsed or refractory

Lili Zhou, Ping Li, Shiguang Ye, Xiaochen Tang, Junbang Wang, Jie Liu, Aibin Liang

《医学前沿（英文）》 2020年 第14卷 第6期   页码 786-791 doi: 10.1007/s11684-020-0751-3

摘要： Factors associated with complete and durable remissions after anti-CD19 chimeric antigen receptor T (CAR-T) cell immunotherapy for relapsed or refractory non-Hodgkin lymphoma (r/r NHL) have not been well characterized. In this study, we found that the different sites of extranodal involvement may affect response, overall survival (OS), and progression-free survival (PFS) in patients with r/r NHL treated with anti-CD19 CAR-T cells. In a cohort of 32 treated patients, 12 (37.5%) and 8 (25%) patients exhibited soft tissue lymphoma and bone marrow (BM) infiltrations, respectively, and 13 (41%) patients exhibited infiltration at other sites. The factors that may affect prognosis were identified through multivariable analysis. As an independent risk factor, soft tissue infiltration was the only factor significantly correlated with adverse prognosis ( <0.05), whereas other factors did not reach statistical significance. Furthermore, the site of extranodal tumor infiltration significantly and negatively affected OS and PFS in patients with r/r NHL treated with anti-CD19 CAR-T cell therapy. PFS and OS in patients with BM involvement were not significantly different from those of patients with lymph node involvement alone. Thus, anti-CD19 CAR-T cell therapy may improve the prognosis of patients with BM infiltration.

关键词： anti-CD19 chimeric antigen receptor T cell     soft tissue     bone marrow     relapsed or refractory non-Hodgkin lymphoma    

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Involvement of p38 mitogen-activated protein kinase in the regulation of platelet-derived growth factor

GONG Xiaowei, WEI Jie, LI Yusheng, CHENG Weiwei, DENG Peng, JIANG Yong

《医学前沿（英文）》 2007年 第1卷 第3期   页码 248-252 doi: 10.1007/s11684-007-0047-x

摘要： The aim of this study was to investigate the role of p38 mitogen-activated protein kinase (MAPK) in cell migration induced by platelet-derived growth factor (PDGF). Western blot was performed to detect the phosphorylation of p38 in NIH3T3 cells treated with PDGF. A Transwell cell migration system was used to determine the effects of PDGF treatment on the migration of NIH3T3 cells and the influence of deficiency on this process in a gene knockout (p38) mouse embryonic fibroblast cell line. On the stimulation of PDGF, the migration of NIH3T3 cells was significantly increased (〈0.001) compared to the control and p38 MAP kinase was simultaneously phosphorylated. Furthermore, the PDGF-induced cell migration was significantly blocked in gene knockout (p38) mouse embryonic fibroblasts (MEFs) (〈0.001) as compared with the wild type cells (p38). p38 MAPK plays an important role in the regulation of cell migration induced by PDGF.

关键词： control     stimulation     mitogen-activated     growth factor     process    

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A carbon efficiency upgrading method for mechanical machining based on scheduling optimization strategy

Shuo ZHU, Hua ZHANG, Zhigang JIANG, Bernard HON

《机械工程前沿（英文）》 2020年 第15卷 第2期   页码 338-350 doi: 10.1007/s11465-019-0572-8

摘要： Low-carbon manufacturing (LCM) is increasingly being regarded as a new sustainable manufacturing model of carbon emission reduction in the manufacturing industry. In this paper, a two-stage low-carbon scheduling optimization method of job shop is presented as part of the efforts to implement LCM, which also aims to reduce the processing cost and improve the efficiency of a mechanical machining process. In the first stage, a task assignment optimization model is proposed to optimize carbon emissions without jeopardizing the processing efficiency and the profit of a machining process. Non-dominated sorting genetic algorithm II and technique for order preference by similarity to an ideal solution are then adopted to assign the most suitable batch task of different parts to each machine. In the second stage, a processing route optimization model is established to plan the processing sequence of different parts for each machine. Finally, niche genetic algorithm is utilized to minimize the makespan. A case study on the fabrication of four typical parts of a machine tool is demonstrated to validate the proposed method.

关键词： Low-carbon manufacturing     carbon efficiency     multi-objective optimization     two-stage scheduling     job shop    

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大数据研究在意大利的远景 Perspective

Bergamaschi Sonia,Carlini Emanuele,Ceci Michelangelo,Furletti Barbara,Giannotti Fosca,Malerba Donato,Mezzanzanica Mario,Monreale Anna,Pasi Gabriella,Pedreschi Dino,Perego Raffele,Ruggieri Salvatore

《工程（英文）》 2016年 第2卷 第2期   页码 163-170 doi: 10.1016/J.ENG.2016.02.011

摘要：

这篇文章的目的在于综述在大数据背景下一些意大利大学正在从事的研究项目。本文不求面面俱到，目的是提供从意大利不同领域收集到的有关大数据管理方面的问题的实际解决方案。

关键词： 大数据     智慧城市     能源     工作机会     隐私    

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标题 作者 时间 类型 操作

Research on the Relationship between Personal-Organizational Values Fit and Job Involvement of the New

Ai-hua Huang,Guo-tao Guo,Hai-xia Qiu

期刊论文

A job-insertion heuristic for minimizing the mean flowtime in dynamic flowshops

Guang GUO, Bo WU, Shuzi YANG

期刊论文

Industry effect of job hopping: An agent-based simulation of Chinese construction workers

Jide SUN, Mian ZHENG, Martin SKITMORE, Bo XIA, Xincheng WANG

期刊论文

Analysis of dispatching rules in a stochastic dynamic job shop manufacturing system with sequence-dependent

Pankaj SHARMA,Ajai JAIN

期刊论文

Energy-aware fuzzy job-shop scheduling for engine remanufacturing at the multi-machine level

Jiali ZHAO, Shitong PENG, Tao LI, Shengping LV, Mengyun LI, Hongchao ZHANG

期刊论文

Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock

null

期刊论文

Astragaloside IV suppresses post-ischemic natural killer cell infiltration and activation in the brain: involvement

Baokai Dou, Shichun Li, Luyao Wei, Lixin Wang, Shiguo Zhu, Zhengtao Wang, Zunji Ke, Kaixian Chen, Zhifei Wang

期刊论文

Perception of people for the risk of Tianwan nuclear power plant

Lei HUANG, Jun BI, Bing ZHANG, Fengying LI, Changsheng QU,

期刊论文

Different sites of extranodal involvement may affect the survival of patients with relapsed or refractory

Lili Zhou, Ping Li, Shiguang Ye, Xiaochen Tang, Junbang Wang, Jie Liu, Aibin Liang

期刊论文

Involvement of p38 mitogen-activated protein kinase in the regulation of platelet-derived growth factor

GONG Xiaowei, WEI Jie, LI Yusheng, CHENG Weiwei, DENG Peng, JIANG Yong

期刊论文

A carbon efficiency upgrading method for mechanical machining based on scheduling optimization strategy

Shuo ZHU, Hua ZHANG, Zhigang JIANG, Bernard HON

期刊论文

大数据研究在意大利的远景

Bergamaschi Sonia,Carlini Emanuele,Ceci Michelangelo,Furletti Barbara,Giannotti Fosca,Malerba Donato,Mezzanzanica Mario,Monreale Anna,Pasi Gabriella,Pedreschi Dino,Perego Raffele,Ruggieri Salvatore

期刊论文